Mesenchymal stromal cell therapy as treatment for ischemic heart failure: the MSC-HF study
نویسندگان
چکیده
منابع مشابه
Cell-Based Therapy of Ischemic Heart Failure
Ischemic heart failure (IHF), heart failure secondary to myocardial infarction, is the number one killer in the US. Despite all the major advances in cardiac interventions, its relevance is on the rise. There is an urgent need for an effective alternative therapy. Stem cells have the potential to ameliorate many chronic illnesses such as IHF. Like any new therapy, several unanswered questions n...
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BACKGROUND The aims of this study were: (1) to show the feasibility of using adipose-derived stromal vascular fraction (SVF) as an alternative to bone marrow mono nuclear cell (BM-MNC) for cell transplantation into chronic ischemic myocardium; and (2) to explore underlying mechanisms with focus on anti-inflammation role of engrafted SVF and BM-MNC post chronic myocardial infarction (MI) against...
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متن کاملEndogenous Cardiac Stem Cell Therapy for Ischemic Heart Failure
Cardiovascular disease remains the number one cause of morbidity and mortality in the world. With great advances in medical and interventional therapies, patients who suffer from acute myocardial infarction have a longer life expectancy than before, but gradually develop chronic heart failure in their later life due to irreversible loss of cardiomyocytes. So far, heart transplantation is the on...
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Correspondência: Domingo Marcolino Braile Av. Juscelino Kubitschek, 1505 15091-450 São José do Rio Preto SP E-mail: [email protected] Milhões de pessoas, em todo o mundo, são portadoras de insuficiência cardíaca crônica e a causa isquêmica uma das mais prevalentes, constitui-se em grave problema de saúde pública. Os atuais tratamentos complementares ao tratamento clínico otimizado, tais com...
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ژورنال
عنوان ژورنال: Cardiovascular Diagnosis and Therapy
سال: 2017
ISSN: 2223-3652,2223-3660
DOI: 10.21037/cdt.2016.11.13